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Words: | Submitted: Mon Apr 24 2006
... melanin in the eye also results in problems with vision. There are two main categories of albinism in humans: oculocutaneous and ocular. In oculocutaneous albinism, pigment is missing from the hair, eyes, and skin. Oculocutaneous albinos are classified as tyrosinase-positive or tyrosinase-negative. Tyrosinase-positive and -negative oculocutaneous albinos possess an autosomal recessive inheritance pattern. Oculocutaneous albinism results from incomplete melanization of the cellular melanosomes. In cases of Tyrosinase positive albinism, the enzyme tyrosinase is present but is unable to enter pigment cells to produce melanin. In tyrosinase negative cases In ocular albinism, only the eyes lack pigment and this is due to abnormalities in melanosome synthesis rather than inadequate melanization. Ocular albinism is transmitted through either an X-linked or autosomal recessive mode. The hair and skin of the ocular albino tends to show a much greater pigmentation than that of the oculocutaneous albino As we've stated before, there are many clear symptoms of albinism including ...
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